Before anything you need to read Berserk. One of the best mangas out and also one of my favorite anime. Battle Royale is also very good. A friend got me hooked on it and I can't stop reading. Both are extremely violent, though. Battle Royale specifically as it also has some gratuitous sex and gore. Characterization is top notch. Still worth a look.
As for comedy, check out Love Hina. I haven't read much of it, but on the few I have read I actually laughed out loud in the store. Cowboy Bebop is always good, but the anime is significantly better than anything the manga could produce.
Another one that looks great is Blade of the Immortal. I have yet to read it, but from what I saw the art looks amazing.
"When angels are forced out of heaven they become devils." -- Viciouis
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