I'm using the original Tropico, without any of the add-ons.
Who knows what the heck the "insert disk 0 with data3.cab" problem is caused by? Why does the game install only the first time, or only sometimes, or sometimes never for different people? Whether it works or not, you never see the data3.cab file on your CD. I looked all over the net for information on this, and found similar problems with different games. Search for "data3.cab" on Google, and you'll see what I'm talking about. The usual answer to people's complaints is: "your CD is defective", or "your CD-ROM settings are wrong", to which I see people reply that the problem still remains unfixed.
I've never seen Mucho Macho either, and I have heard that it has two CDs, but in that particular case, my guess would be that Mucho Macho really DOES need a data3.cab.
In the case of the original Tropico, it's clear that the game reallly DOESN'T need a data3.cab; the game plays fine (if you get it to install) without data3.cab, and that's also why you don't see it on the CD. It's just that, for some reason known only to God (and maybe a few programmers), the original version THINKS it needs data3.cab.
To illustrate that point, try making a copy of the data1.cab or data2.cab file on the CD, paste it to your hard drive, and rename it data3.cab. When the install asks for data3.cab, point it to the file on your hard drive you just renamed. You'll notice it doesn't say "invalid file", but proceeds to ask you for a "data4.cab". Rename the file on your HD to data4.cab, and give the installer that file, and it asks you for a "data5.cab"......and so on, and so on. The installer will keep incrementing to infinity, because it THINKS it needs additional information, but it really doesn't. There's a reason why the installer behaves this way, the question is, what is it?
In my case, after pulling my hair out trying to install for four hours, deleting the registry keys somehow tricked the installer into working. The game is up and running on my machine, with no data3.cab, and works perfectly.
Uninstalling via the Control Panel as Breakaway Mac suggests could probably remove those registry keys the same way, and would be preferrable to editing the registry directly, so if that works, go for it. It wouldn't surprise me at all that the uninstall on the CD doesn't work, for the simple reason that, Tropico's programmers may want to leave some registry keys behind, to keep track of a person's install history or for security purposes, or whatever.